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The strength of Bayesian inference lies precisely in its ability to incorporate existing knowledge into statistical specifications.
Enrichment analysis is a convenient way to incorporate existing knowledge from biological reference networks without analysing graph topology directly.
Furthermore, recent efforts have also been made to incorporate existing knowledge about network biology into data-driven network inference [ 19].
This can be solved by a Bayesian regression where we can incorporate existing knowledge by tuning the prior on β.
Moreover, it is possible to incorporate existing knowledge about protein interactions and protein binding interfaces in the point matching procedure, providing an ideal framework for comprehensive data integration.
We therefore do our best with estimating them using existing data from other viruses or via rough estimates that incorporate existing knowledge about influenza.
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Our proposed technique incorporates existing knowledge about the performance of fMRI designs, and its usefulness is shown through simulations.
Second, this novel hypothesis on migraine pathophysiology incorporates existing knowledge into a new, more complex framework, rather than refuting prior studies.
Although understanding of the mechanisms is incomplete, the models used to predict drought impacts could be significantly improved by incorporating existing knowledge.
To evaluate the impact of incorporating existing knowledge into the model, we tested another version of BEST in which we fixed the indicator variables of five real target genes and five true foreground experimental conditions as 1.
Here, we describe a semi-supervised version of the CoSBI algorithm (SS-CoSBI), which incorporates existing knowledge of histone codes into the learning process.
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