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Most emergent concerns in the Finnish economic evaluations of cancer treatments were related to the inconsistent time frame of costs and effectiveness, utilities, and comparability of the patient populations.
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The downside includes cultural resistance to Good Clinical Practice (GCP), clinical research process real-time compliance, inadequate information systems leading to unpredictable project milestones, a "no clock" application process in the regulatory machinery, and inconsistent time frames for export/import of clinical trial materials at the border.
In their review of ICU studies, McAdam and Puntillo [ 10] conclude that depression affected 15%-35%-35%patient family members, however, they too are comparing studies with inconsistent time frames used to examine symptoms, different medical conditions, and assessment instruments.
While the vast majority of responses to our questions yielded consistent answers, we did find 34 respondents who gave inconsistent responses on questions about the time frame they would most like to know (e.g., choosing 5 days as the "most important" time frame, but strongly disagreeing with the idea of considering a patient's risk of clinical deterioration while in the hospital).
A vague time frame?
How about time frame?
The time frame also matters.
"There's no time frame.
11 time frame.
"The time frame?
It depends on the time frame.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com