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Nitrogen fixation was an example of inconsistent pathways (Ring 5).
Unspecific and inconsistent pathways are replaced by more appropriate pathways.
Pathways were categorized into consistent pathways with RI > 0.9 and inconsistent pathways with RI < 0.7.
Out of the 706 pathways in Bacteria and Archaea, 31% were consistent pathways and 26% were inconsistent pathways.
In the case of FindPath, the fact that the topological approach does not take stoichiometry into account might produce some inconsistent pathways.
In the context of metabolic engineering (i.e. enumerating pathways between native metabolites and heterologous targets) we found only few inconsistent pathways (less than 1% of the 23564 enumerated pathways).
Similar(54)
Importantly, the activation of XBP1 in a proapoptotic scenario such as our model is by no means inconsistent with known pathways of UPR regulation.
Obstacles in funding pathways, inconsistent support by government departments, difficulties with staff retention and erratic delivery of training programs have resulted in mixed success of the national NSV program.
The inconsistent referrals to pathway names further strengthen the necessity of integrating the pathway-gene and pathway-gene pair relationships from different databases into one unified and comprehensive information source.
(i) The inconsistent referrals to pathway names are partially caused by the different levels of emphases on the same pathway in different databases.
The problems of inconsistent referrals to pathway names and incomprehensive data from different databases have been solved by the integration of pathway-gene and pathway-gene pair relationships into a unified and comprehensive data source.
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