Sentence examples for incompletely retained from inspiring English sources

For example, determining essentiality and function of incompletely retained complexes would provide an excellent means by which to test both conservation of function and the importance of retaining composition.

These data suggest that all the mutants, except R1180P and R762X found in the culture medium, were incompletely glycosylated and retained in the ER.

In a process referred to as quality control only correctly folded proteins are exported to the Golgi complex, while incompletely folded proteins are retained in the ER to complete the folding process or be targeted for degradation [ 55, 56].

Only correctly folded proteins are transported out of the ER whilst incompletely folded proteins are retained in the organelle to complete the folding process or to be targeted for destruction (Rapoport 2007).

In mammals, calnexin provides chaperone activity to retain incompletely glycosylated proteins in the ER, functioning as a component of the glycoprotein quality control system in the ER [ 70].

Calnexin has an important role in glycoprotein folding as a lectin-like chaperone; together with calreticulin, it performs quality control by retaining incompletely folded or misfolded proteins in the ER.

This invalidation step will minimize the spurious inclusion of incompletely processed transcripts in the retained intron class.

The microstructure of the coatings was found to consist of two distinct regions; one of the regions was completely melted and quenched as splats, and the other was incompletely melted with a particulate microstructure retained from the starting agglomerates.

Upon folding, native proteins can exit the ER by the secretory pathway, whereas misfolded proteins and incompletely assembled protein complexes are generally retained by a protein quality control machinery [1].

For one, incompletely spliced or processed RNAs are retained at their sites of transcription and not released into the nucleoplasm for export.

Since only correctly folded Ig can be secreted from the cell, incompletely folded or misfolded Ig is either retained in the cell for further folding, or targeted for proteasomal degradation [22 24].