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For example, the incomplete segregation information provided by those DArT markers segregating in a 3 1 ratio (intercross) results in an exponential increase of marker-ordering calculations compared to fully-informative co-dominant markers [ 37].
The simplicity of the original Mendelian system has now to be supplemented by such conceptions as those of "imperfect dominance," "incomplete segregation," "compound allelomorphs," and the like.
Segregation analysis revealed incomplete segregation in a large kindred.
Therefore, the incomplete segregation does not necessarily diminish the importance of p.Met1? as a HPCX 1 risk variant.
We confirmed the D153G mutation in separate amplification reactions and also in the patient's mother but not in the maternal aunt, indicating an incomplete segregation pattern.
However, clinical screening of the CHEK2 variants has not yet been justified due to unclear clinical consequences related to incomplete segregation of the variants with BrCa in the high-risk BrCa families [ 39, 40].
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In fact, the cells damaged in the prometaphase showed incomplete chromosome segregation (Fig. 6B).
A higher proportion of miR-128 transfected cells in the supra-G2/M phase of the cell cycle may be indicative of incomplete chromosomal segregation due to alterations at the mitotic/metaphase checkpoint.
The absence of pectinase genes in the cluster was further confirmed by PCR with primer pairs targeting pecA, pecB, and pecR within the cluster to eliminate the possibility of contamination by merodiploids resulting from incomplete genome segregation.
One family presented with complete co-segregation, but the other with incomplete co-segregation.
While complete co-segregation was found in 34 families, incomplete co-segregation was more commonly observed, revealing genetic heterogeneity (affected but not carriers) and incomplete penetrance of the mutation (carriers but unaffected men).
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