Sentence examples for incomplete folding of from inspiring English sources
It is now known that blocking glycosylation could result in improper or incomplete folding of many polypeptides.
We hypothesized that the formation of non-native disulphide bonded aggregates of mutant V194D matrilin-3 was the direct result of delayed or incomplete folding of the central β-sheet of the A-domain that results in prolonged exposure of the thiol groups of the two terminal cysteine residues (Cys77 and Cys263).
In the chaperone subunit complexes, the chaperone inserts part of a β-strand (strand G1) in the subunit's groove and thus complements in trans the incomplete fold of the pilus subunit, a process called donor-strand complementation (Choudhury et al, 1999; Sauer et al, 1999).
The observed deviation results from incomplete folding, the presence of impurities, and the stress-induced partial loss of function during purification and storage.
These findings support the preservation of proinsulin's aggregation-prone nature and low relative folding rate that permits the plentiful production of non-monomer forms with incomplete folding.
A bad or incomplete fold can lead to heartbreak at the end.
The remaining 239 tumors had incomplete results, due to folding of the core, loss of tumor material or insufficient amounts of invasive breast cancer for scoring.
Addition of targeting sequences to GFPs or fusions to proteins of interest can exert a considerable strain on the folding of a given fluorescent protein that often results in incomplete targetings or unsuccessful protein fusions.
Some require hand folding of unique pieces or special folds.
Inappropriate mRNA structure and gene copy numbers, limits in transcription, translation and protein translocation into the ER, incomplete protein folding and inefficient protein targeting to the exterior of the cell are major bottlenecks encountered in secretory expression of heterologous proteins.
Similarly let e incompl, K (s ) be the prediction error estimated by incomplete K-fold CV, i.e. when the data preparation step(s) of interest is performed before CV, using the whole dataset.
