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Although this might be due to the incomplete differentiation of ES cells or the ES cells slightly differentiated during the selection step, so that some types of differentiated cells can not be distinguished from ES cells, it also possible that the recognition specificity to a particular cell is a relative value.
A lack of cryovolcanism would be consistent with geophysical inferences of a relatively quiescent interior: incomplete differentiation, only minor tidal heating, and possibly a lack of internal convection today.
One speculation can be, SMN1 deletion in SMA may lead to incomplete differentiation of neurons, and decreased viability of cells and immature forms may escape apoptosis, which can develop malign transformation.
The piwi class of genes was identified long ago as encoding regulatory proteins that are responsible for the maintenance of incomplete differentiation in stem cells and also in preserving the stability of cell division rates in germ line cells, a quite important set of processes related again to all stages of development, growth and differentiation (Brennecke et al. 2007).
Whilst a fall in neuron numbers seems a common pattern during postnatal development, several authors have nonetheless reported an increase in neuron number, which may be associated with any one of a number of possible processes encapsulating either neurogenesis or late maturation and incomplete differentiation.
This suggests that antigen presentation by liver parenchyma cells results in incomplete differentiation of CD8+ T cells.
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Considering that OS cells appear to be somehow 'frozen' in a state of incomplete osteogenic differentiation [ 26– 28], a better insight into specific gene regulation during OS differentiation may help remove this block and may have therapeutic value.
When HGF, nicotinamide, or dexamethasone was added to MSCs individually, incomplete hepatocyte differentiation was achieved; the obtained cell populations contained progenitors that expressed both hepatic (ALB) and biliary (CK19) markers as well as AFP.
Such TFs prefer 5-TAA/TTA-3 elements (overrepresented in promoters of psoriasis-decreased DEGs), and their decreased expression in psoriasis may contribute to incomplete KC differentiation, thereby favoring KC proliferation [83,84].
Intersexuality is the blanket term for overt, variations or incomplete sexual differentiation.
Considering the incomplete morphological differentiation as well as the comparatively low mitochondrial distances and recent divergence times, we conclude that C. mapale and Cathorops sp. represent a case of incipient speciation.
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