Sentence examples for incomplete complementarity from inspiring English sources

First, animal miRNAs have been found to mediate mRNA degradation even when the target sites have incomplete complementarity to them [20] [22].

However, it has been well reported that small RNAs can be effective against single and multiple target mRNAs with incomplete complementarity [34], [35].

If the miRNA binds with incomplete complementarity then it causes translational repression of the mRNA.

Duplex RNA were designed to have incomplete complementarity with the 3'UTR sequences of both target genes.

In contrast, in humans, miRNAs bind to mRNA targets with incomplete complementarity, which results in mRNA destabilisation and translational inhibition.

Since miRNAs usually pair with incomplete complementarity to their targets, bioinformatic approaches to identify targets are limited and functional analysis is required to prove mRNA:miRNA interactions.

Sixteen of the 46 genes had incomplete sequence complementarity to a corresponding gene using BLAST searches in Ensembl genome browser based on the human build 17 and were excluded from further analysis, leaving 30 probes for technical validation.

In the RISC complex, a guide RNA strand is retained that captures target mRNA through complete or incomplete sequence complementarity.

The value of this computationally derived dataset becomes apparent by comparison with proteomics studies on the parasite invasion complex and secreted organelles (Table 2): based on experimental validation, the low degree of overlap suggests complementarity of incomplete datasets, rather than poor quality data.

Moreover, in most animals, regulatory RNAs such as miRNAs have incomplete homology with their target sequences [ 31] and, therefore, our predictions based on perfect complementarity may have missed some potential targets in the host genomes, again leading to false negative results.

It is complementarity, not complimentarity.