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After the exclusion of 86 patients with pathological HF (metastatic bone cancer, multiple myeloma, Paget's disease) or primary hyperparathyroidism and 15 patients in whom data were incomplete, a total of 746 patients (536 women and 210 men) were included in the analysis.
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After removing incomplete questionnaires, a total of 788 respondents (230 physicians, 478 nurses, and 80 administrators) from 42 hospitals had successfully completed the questionnaire.
After removing incomplete questionnaires, a total of 78 respondents from 16 PHCCs provided completed surveys (17 physicians, 46 nurses, and 15 non-care providers).
The original sample consisted of 2499 students, and after exclusion of incomplete questionnaires, a total of 2,449 participants were included in the analysis: 1,254 boys (51.2%) and 1,195 girls (48.8%).
As shown in figure 1, 32 patients were excluded due to the presence of one or more exclusion criteria and 27 questionnaires were further excluded from analysis due to incomplete information; a total of 411 patients were finally included in the study (figure 1).
After excluding cases with familial adenomatous polyposis, multiple primary colorectal cancer, other malignancies at the same time or previously, or N1c stage disease, cases in which the patient underwent preoperative radio-chemotherapy or experienced recurrence or death within 3 months, and cases that were lost or had incomplete information, a total of 145 cases were included in this study.
Three questionnaires were excluded because of incomplete information, giving a total of 98 questionnaires (84.5 %).
One hundred four of these women were excluded from the analysis because of the incomplete data and a total of 403 women were used for the final analysis.
We also expanded this incomplete dataset to a total of 28 protein-DNA interactions by looking in the nuclear receptor Factsbook [ 67].
After data collection 34 questionnaires were excluded before analysis (due to questionnaires being >10%% incomplete), resulting in a total of 431 participants.
Using the Cochran (1977) [ 43] statistical formula, the minimum sample size was calculated, but a 10% was added to amount for non response and incomplete questionnaires giving a total of 191 but 200 dentists were finally recruited for this study.
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