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2. While "representation" and "imitation" are standard meanings of "mimesis," the inclusion of "expression" in a list of possible meanings of the term might seem odd.
UGET is an invaluable resource for a geneticist that permits the rapid inclusion of expression criteria from one to hundreds of genes in genomic intervals linked to disease.
To be able to further increase the enrichment for these cancer specific methylated markers, the inclusion of expression microarray data from normal tissue in the relaxation ranking algorithm analysis might be helpful.
Taking into account that the DFC test was not optimized for variance stabilization (FFPE sample sets are seldom small), its performance can potentially benefit from the inclusion of expression dependent stabilization of variance.
Cluster 2 (blue) is robust to the additional inclusion of expression data, indicating that there is no significant disagreement amongst the three datasets regarding the existence of this cluster.
In contrast to the addition of genetic deletions, inclusion of expression data from the FL treatment experiment did not impact network interactions to alter ERG11, ERG6 and ERG5 ranks.
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The expression of HER2 was an independent prognostic predictor of RFS (P = 0.017, HR; 1.980, 95% CI; 1.132-3.464 .To test the impact of the NGF/HO1 expression pattern on OS and RFS of BRCA patients, multivariate analysis was performed with the inclusion of NGF/HO1 expression instead of the individual expression of NGF and HO1.
NP cell expression levels were compared with the average expression levels of AC and AF cells (NP/AC&AF) to identify potential NP-specific genes (Table 5), whereas NP cell expression levels and AC expression levels (NP/AC) were compared, without inclusion of AF expression levels, to identify potential IVD-specific genes (Table 6).
One possible strategy for the inclusion of gene expression data in the analysis would require several steps: from rat phosphorylation levels to rat gene expression data to human gene expression to human phosphorylation levels, with the possibility of significant and unknown systematic and stochastic errors.
Inclusion of the expression rates makes the result slightly worse, except for the least squares where the correlations are equal.
In addition, analyses can be easily expanded by inclusion of additional expression profiles, such as, a set of E2 replacement ArKO ovarian genes or refined by identifying which ER subtype is responsible for specific E-dependent ovarian genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com