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Two review authors independently assessed studies for inclusion; discrepancies were resolved by discussion or by a third party.
The Covidence software platform, 34 will be used to facilitate independent screening and selection, and to identify screening and inclusion discrepancies.
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Titles and abstracts were sifted by two reviewers independently with discussion used to resolve any inclusion / exclusion discrepancies.
Two review authors independently assessed the selected full-text articles for inclusion, resolving any discrepancies by consensus.
Two independent reviewers determined whether studies met the inclusion criteria, and discrepancies between reviewer decisions were resolved in consensus.
For LCC, despite some diversities in outcome definition, study inclusion criteria (and discrepancies in their application), and the dates of search end (which have been detailed in the Table S1 ), the overall vaccine efficacy coming from RCTs (considering all vaccine types) was relatively high, ranging from 59%to75%5% across all meta-analyses.
Three reviewers (GA, PS, VSH) independently extracted the data from relevant studies, and discrepancies about inclusion were resolved by VSH.
The review team resolved any discrepancies in inclusion through consensus.
Discrepancies regarding inclusion and extraction were then resolved by consensus.
Their inclusion, however, brings about discrepancies in funds received.
Any discrepancies regarding inclusion were discussed among all the three authors until consensus was reached.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com