This includes to our knowledge the first reported use of prednisolone in Africa to manage a severe paradoxical reaction related to BU treatment.
We included, to our knowledge, all published methods where an implementation was available: MADS, MIDAS, SI [ 7], PAC [ 7, 14], ANOSVA, ARH, SplicingCompass [ 15] and FIRMA.
The key strength of this retrospective analysis is the large population of more than 4,000 patients included, to our knowledge the largest consecutive cohort of self-monitoring patients studied in Europe.
Further strengths include to our knowledge the largest sample from a general population survey to date, with a wide age range, high attendance, comprehensive assessment of lifestyle factors, and clinical examinations using standardized and validated methods by trained health professionals, performed within a short time frame.
Our study has many strengths including being, to our knowledge, the largest validation study of severity-of-illness scores in Brazil and using more contemporary data from several centers countrywide.
His research on rhabdoviruses and arenaviruses led to his first 7 scholarly publications, including contributions to our knowledge of the pathology of Lassa fever, an archetypal emerging infectious disease.
Taking the US as a comparison example where hyperbaric oxygen therapy was rarely used, although some US alternative physicians have extended the use of this treatment to include tinnitus, to our knowledge tinnitus is not an indication that is approved by the UHMS Hyperbaric Oxygen Therapy Committee nor is it reimbursed by US medical insurance (e.g. Medicare).
Although several studies reported TB-HIV co-infection in many African countries including Ethiopia (8– 10), to our knowledge, there are no reports on TB-HIV co-infection from pastoralist areas.
We also show in vivo pathological and physiological relevance for these findings including, what is to our knowledge, the first ever vertebrate model of polyglutamine disease which allows quantification of changes in autophagic flux in conjunction with levels of pathological autophagic substrates.
Among existing models of lung cancer prediction, no one included asbestos exposure to our knowledge.
