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We now include supplemental data that monitors the responsiveness of an AKAP18RBS-pro-AKAR containing two proline substitutions in the AKAP18 anchoring helix that abolish binding to PKA.
Include supplemental information.
Future work should consider if the performance of the models can be further improved by including supplemental measurement data, GPS diagnostic parameters, and detailed points-of-interest (POI) information.
The survey includes nationally representative data from 4,826 households, including Supplemental Nutrition Assistance Program (SNAP) households, low-income households not participating in SNAP, and higher income households.
data availability: the ToxCast data sets, including descriptions, supplemental data and associated publications are available from the U.S. EPA ToxCast website.
The work described in the paper (including the supplemental data) is exciting for many reasons.
Complete description of the EMSA protocol is included in supplemental data.
Complete description of the isolation protocol is included in supplemental data (Methods S1).
An example of fixed and embedded colon tissue imaging is included as supplemental data, which clearly shows 3D crypt structures and collagen SHG (Figure S4).
The sequence alignments for these dataset could also be included as supplemental data.
A detailed list of the genes in the groups is included as supplemental data.
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