It is important to note that although the genes identified in this study are conserved across different cultivars, the differences between cultivars can also be substantial, including substantial differences in stress tolerance.
It is important to note that although the genes or expression responses identified in this study may show conservation across different stresses in different cultivars, the basal differences between cultivars can also be substantial, including substantial differences in stress tolerance.
Moreover, this variation may include substantial differences in gene content and gene structure, as was observed in the gene deletion analysis of the PCR data in the present study.
The reasons for the observed resistance gap are multifactorial and include substantial differences in physicians' and patients' attitudes towards antibiotics; sociocultural and economic factors; and disparities in regulatory practices.
11 In summary, under the conditions studied, rifaximin appears to be safe and well tolerated in the treatment of non‐C IBS – with no increased risk of infections, including C. difficile infection and no substantial differences in any AEs vs. placebo.
[ 7] However, the trial had substantial differences in baseline characteristics including gender and condition at birth suggesting the results should be treated with caution.
In comparing our approach in children with published adult studies, we find substantial differences in glycaemic management, including higher insulin requirements and shorter duration of treatment in children [ 35].
For example, the category Asian Pacific Islander includes several distinct ethnic groups that have substantial differences in genetic backgrounds.
At this stage it was clear that substantial differences in studies – which included differences in national or international scope, design, setting, timing, sample bases, and objectives – precluded a formal meta-analysis.
Sensitivity analyses of crude and adjusted linear regression models including only those participants with complete NPAD-d questionnaires did not reveal substantial differences in results.
Substantial differences in these associations were not observed in sensitivity analyses including potentially heteroplasmic participants.
