Exact(3)
Reprogramming involves de-novo establishment of chromatin domains, including resetting the characteristic features of pericentric heterochromatin, essential to progress through the first embryonic mitosis.
The photopigment melanopsin has been suggested to act as a dominant photoreceptor in nonvisual photoreception including resetting of the circadian clock (entrainment), direct tuning or masking of vital status (activity, sleep/wake cycles, etc)., and the pupillary light reflex (PLR).
Somatic cell conversion to the iPSC state is accompanied by epigenetic remodeling, including resetting of the chromatin structure and methylation states of DNA and histone.
Similar(57)
It may be a life-cycle phenomenon, like sexual reproduction, that includes resetting the epigenetic clock each generation.
Some of the other processes that might contribute to phase slips in the basal ganglia include resetting by cortical inputs (Doyle Gaynor et al., 2008) and spike-timing dependent depression (Ahn and Rubchinsky, 2013).
These include resetting the cellular framework; alternating the composition, structure and function of the plasma membrane; synthesizing cryoprotectant molecules such as soluble sugars, sugar alcohols and low-molecular-weight nitrogenous compounds; decreasing the ratio of free water content; improving the scavenging activity of reactive oxygen species (ROS); and introducing antifreeze proteins.
Awareness of the threat online surveillance and censorship poses to fundamental rights has spread across different sectors, with political and civil movements including "Reset The Net", promoted by Edward Snowden and the inventor of the world wide web, Tim bothers-Lee, bofh of whom encourage the adoption of VPNs as a means of securing personal privacy.
We profiled an extended panel of samples, including reset cells and standard counterparts from H9 and two independent iPS cell lines, in addition to those profiled by RNA-seq above.
A security lapse has exposed a massive database containing tens of millions of text messages, including password reset links, two-factor codes, shipping notifications and more.
Of course we should keep pressing others on the issues of key concern to us including modernizing economies, resetting currencies, enforcing sanctions on Iran and North Korea, and doing their part on climate change among other high priority issues.
A lot of water has passed under the bridge since then, including the "reset button" being pressed by President Barack Obama in terms of relations between the US and Russia.
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