Reasons for the large variation in ARDS incidence are unclear, and may include major differences in demographics and healthcare delivery systems.
They primarily include major differences in heart physiology compared with humans and a limited lifespan which precludes long-term follow-up assessments.
Possible reasons for the lack of external validity are multiple and include major differences in the amount of intravenous glucose infused, the frequency of use of enteral nutrition and possibly a lower 'commitment' to TGCIIT by centres other than Leuven.
Some notable genetic variation, however, was also observed in these porcine C. pecorum strains including (i) major differences in the number of PLD genes and; (ii) the presence of a third copy of the cytotoxin gene in the L71 strain, as summarised in Fig. 2.
In breast cancer, five molecular subtypes with prognostic impact have been established based on gene expression patterns, of which luminal A/B and basal-like tumours have the most reciprocal gene expression profiles as well as major differences in clinical parameters, including survival (Perou et al, 2000; Sorlie et al, 2001; Naume et al, 2007).
In contrast, prior studies showed no major differences in the individual FAs, including PUFAs (percentage of total FAs) between GDM and control subjects (5).
Among economists that use genetic markers as instruments, there are major differences in how these variables are included in the first stage.
We did perform a sensitivity analysis including only cases from 2005 onward but did not find any major differences in results (data not shown).
Major differences in the transcriptomic data derived from rodent astrocytes included a lack of activation of VDR-mediated signaling pathway.
A comparison of women included in the 2006 ANC surveillance survey and those in the 2005 06 ZDHS reveals major differences in their characteristics.
