Investigations have led to reform, including major changes to the department and various oversight bodies, the creation of an online database of police misconduct, and the firing of police superintendent Garry McCarthy.
Mélenchon's so-called "Plan A" is a collective renegotiation, by those who want it, of the EU's treaties and agreement on fundamental reform, including major changes to the euro.
The objective is to ensure a stable and flexible operation when the plant is affected by various disturbances, including major changes in the production rate and in the quality of raw materials.
Edward D. Breen, who became chairman of Tyco last year, attended the academy last fall and used it as a sounding board for some monumental changes he was considering for the company, including major changes to the board of directors, he said in an interview.
HARTFORD — Gov. Dannel P. Malloy proposed a broad set of education initiatives, including major changes to teacher tenure, on Wednesday in his second State of the State address, a speech that found his efforts split between unfinished business from his first year in office and a new agenda for his second.
It is also conceivable that shifts in urban form and traffic flows, including major changes such as growth in out-of-city shopping malls in the 1990s, may have changed the movement patterns of potential targets and offenders in ways that reduced street crime.
He has played a major role in the week-old Trump administration, helping the president to draft a flurry of executive orders including major changes in immigration policy.
Years after the end of the worst recession since World War II, which prompted deep service cuts, transit agencies are still trying to figure out where their riders have gone and what can be done to bring them back, including major changes to routes and schedules.
The reannotation resulted in changes to 85% of gene models, including major changes in 40% of predicted proteins, without significantly affecting the number of genes predicted.
Multiple stimuli, including major changes to culturing conditions, insult with agents disrupting protein folding, and RNAi of critical mRNAs encoding factors essential for endocytosis and cell surface maintenance, elicited extremely limited changes to the transcriptome.
