However, these metal nanoparticles exhibit certain limitations including limited availability, high cost and generation of ill effects such as skin allergy, eye irritation etc. Hence metal nanoparticles have considerably faded its importance for dye degradation processes (Vinothkannan et al. 2015).
However, most of these studies describe preliminary results and went almost unnoticed for several reasons, including limited availability of the original documents (Smith 1995), limitations in the experimental setup, or low number of yeast strains screened.
However, the adult OVX rabbit model has many limitations which preclude its use for routine drug screening, including limited availability of skeletally mature aged rabbits, requirements for surgical manipulation, long study duration and a large body weight that requires preparation of large quantities of agents.
There are numerous challenges associated with providing fistula repair services in developing countries, including limited availability of operating rooms, equipment, surgeons with specialized skills, and funding from local or international donors to support surgeries and subsequent post-operative care.
The internet has the potential to reduce barriers to accessing services, including limited availability of skilled professionals, geographic isolation, the cost and inconvenience of travel and child care, and limited flexibility in work schedules [ 12].
Challenges in HAND research, including limited availability of brain tissue from HIV patients, variation in HAND study protocols, and virus genotyping inconsistency and errors, however, have resulted in studies with insufficient power to delineate molecular mechanisms underlying HAND pathogenesis.
Additional limitations of this study include limited availability of clinical data in the RA cohort used for the initial gene-signature discovery owing to the retrospective nature of interrogation of clinical chart data after sample collection from joint surgery, and a lack of consent for chart review in some cases.
Disadvantages of MRI include limited availability, the long acquisition times and the need for deep sedation or general anaesthesia in young children, which may involve high risks in patients with airway compromise.
Barriers to effective treatment include limited availability of skilled clinicians, direct and indirect costs of treatment, and difficulty attending treatment during office hours.
These include limited availability of human material, no established protocol to isolate β cells from human pancreatic islets and the lack of human beta cell lines.
Underlying causes of poor health for women and children include limited availability of timely and reliable health information for decision-making and poor access to and use of health facilities.
