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The exact mechanism of both polymorphisms is not completely clear, but they are expected to have various effects including affecting the insulin sensitivity of peripheral organs [ 11, 23].
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Patients excluded owing to inability to provide informed consent had higher severity of illness scores than those included, affecting the trial's external validity.
Possible TNP-470 mechanisms on endothelial cells include affecting the cell cycle through p53 activation by binding to methionine aminopeptidase (MetAP-2), preventing Rac1 activation and induction of p21 (CIP/WAF).
Risk of unauthorized disclosure or modification of corporate data can impact in different ways, including affecting operations, the public image and/or the firm's legal/compliance exposure.
We included affected and unaffected individuals following the same criteria used for our cases.
Scientists have developed more than 500 mouse models of human ailments, including those affecting the heart and central nervous system, as well as diabetes, cancer and cystic fibrosis.
The revised plan drops some of Mr. Malloy's planned tax increases, including some affecting the boating and car industries.
Negotiators meeting here in a downtown hotel have advanced this week on key issues including rules affecting the auto industry and the settlement of investor disputes.
There have been no leaks in high-stakes financial cases including ones affecting the tobacco industry.
Other genetic variants are also in play, including those affecting the production and/or reception of dopamine (a neurochemical that directly stimulates the brain's pleasure center).
Then, the epidemiology of maternal smoking during pregnancy is covered including factors affecting the likelihood of smoking cessation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com