In February, researchers in Europe and the United States revealed they were able to sequence his genome -- his complete DNA -- and found he suffered from many of the ailments people still suffer from today, including a predisposition to heart disease.
Experimental and epidemiological data suggest that gestational diabetes may have long-term consequences for both baby and mother, including a predisposition to obesity, metabolic syndrome, and diabetes later in life (Boloker et al. 2002; Reece et al. 2009).
Personality traits associated with this group included a predisposition to procrastinate and put off things that need doing.
Individuals with germline mutations in the Shh receptor PTCH have Gorlin syndrome, which includes a predisposition to medulloblastoma [ 3, 47].
Characteristics include a predisposition to benign and malignant colorectal and duodenal tumors, as well as rare malignant brain tumors, thyroid cancer, and hepatoblastoma.
If the lipids themselves have physical properties that might influence their function, these could include a predisposition to organize into different domains, possibly recruiting other lipids and/or proteins to these domains in cells.
Given that children who live in deprived neighbourhoods are likely to include a predisposition to experiment with smoking [ 29], further insight into factors that influence smoking-related cognitions in these groups can provide additional knowledge to inform the development of interventions.
HPRL in these patients can be caused by general stress associated with the illness experience [ 79], or by a pre-existing vulnerability [ 168], including a genetic predisposition [ 170].
The etiology of PFD is probably multifactorial, including a genetic predisposition to connective tissue abnormalities, vaginal childbirth with damage to the innervation of the pelvic floor muscles, estrogen deficiency, and aging effects [ 1].
The situation is complicated by the fact that a mental disorder such as schizophrenia may be caused by a combination and interaction of several factors, including a probable genetic predisposition to develop the disease, a postulated biochemical imbalance in the brain, and a cluster of stressful life events that help to precipitate the actual onset of the illness.
A combination of multiple factors, including a strong genetic predisposition and environmental factors, are considered to contribute to the developmental pathways to borderline personality disorder (BPD).
