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Traditional phase I design includes dose escalations, by cohort, until significant toxicities are observed.
Based on these results, current guidance includes dose adjustment according to the type and duration of CRRT provided [ 14].
First, the interaction between dose, pharmacokinetics (PK), and toxicities results in a realized dose regimen for each patient that includes dose reductions.
Drug utilization and enteral nutrition information is available by day of stay, and includes dose quantity (number of doses given), dose strength (for each individual dose given), dosing regimen (total dose administered), and hospital-reported cost.
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Mr. Xalxo says he prepares the rice from a recipe that includes doses of cumin, ginger and garlic.
This includes doses that are not licensed for use in the UK, which could be brought in subject to regulatory issues.
84 Another lenalidomide-containing salvage regimen with proven efficacy accompanied with mild toxicity, which may be beneficial to frail MM patients, includes dose-adjusted lenalidomide-cyclophosphamide-prednisone.
This data also includes doses given to children born after the intervention period, forming part of the comparison group.
Need to include dose information in a form understood by referrers and patients.
Survival outcomes and toxicity of various approaches to radiation dose intensification, including dose escalation and hyperfractionation, will be assessed.
The parameters evaluated included dose homogeneity and conformality, dose to organs at risk (OARs), and delivery efficiency.
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