Thus it is unknown whether APP joins viral particles during packaging inside the cell, or during the procedure to isolate viral particles, which includes disruption of infected cells, centrifugations and sucrose density fractionation, which could redistribute molecules not normally together.
Therefore, these results support the view that ranalexin's mode action includes disruption of the staphylococcal cell wall.
This 'synaptic autism pathway' notably includes disruption of SYN1 that is associated with epilepsy, autism and abnormal behavior in both human and mice models.
The mechanism of this synergistic apoptotic effect on MM cells is multifactorial and includes disruption of protein degradation and inhibition of the interaction of MM cells with the tumor microenvironment [ 217].
The mechanism of action of cryotherapy includes disruption of cell membranes by the formation of intracellular ice crystals during the freeze cycle and vasoconstriction, endothelial damage, thrombosis, and tissue ischemia during the thaw cycle [ 22, 23].
Gonadal intersex includes disruption of the gonadal duct, where the male duct is feminized to form a female-like ovarian cavity, and/or the presence of both male and female germ cells within the same gonad (Nolan et al. 2001).
