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3 Such studies will be enhanced by more detailed phenotypic characterisation of study cohorts that includes body fat distribution, as this is known to be a significant risk factor for other chronic diseases, such as cardiovascular disease and type II diabetes.
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The aim of this study was to assess the effect of growth hormone (GH) replacement therapy on lean body mass (LBM) and other variables including body fat mass, serum lipids and quality of life measures in GH-deficient Japanese adults.
However, in addition to heart rate and acquisition-related confounders, isolated post-contrast T1 values are influenced by a number of factors, including body fat percentage, reduced renal function, altered haematocrit, native T1, delay time in measurement after contrast administration and gadolinium characteristics (dose, concentration and water exchange rate).
However, in that study, the influence of waist circumference and body composition, including body fat and muscle, was not adjusted.
The body composition including body fat percentage, skeletal muscle mass and bone mineral content was quantified with dual energy X-ray absorptiometry (DXA; Lunar, GE, Fairfield, CT, USA).
38 Health-related physical fitness components are level of endurance, strength, flexibility, and body composition including body fat percentage and lean muscle mass.
Main outcome measures Primary outcome measures included body fat (sum of four skinfolds), aerobic fitness (shuttle run test), physical activity (accelerometry), and quality of life (questionnaires).
Although aldosterone was related to metabolic factors, including body fat % and fasting plasma glucose in our female subjects, the relationship between aldosterone and adiponectin remains unclear.
As leptin may be positively correlated with the levels of total body fat, limb fat, and trunk fat [ 41], the predictive value of our model might have been improved if we had included body fat redistribution in our analysis.
In multivariate regression adjusting for age and sex, and then including body fat percentage (models 1 and 2), the association of log fasting insulin with PAEE remained highly statistically significant (β = −1.87, p < 0.001 and β = −0.875, p = 0.006 respectively).
The explained variance in log fasting insulin varied between 8 and 10% for the models excluding body fat percentage (models 1, 1a, 1b and 1c) and between 26 and 28% for the models that included body fat percentage (models 2, 2a, 2b, 2c).
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