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Reasons for inevaluability included protocol ineligibility (n=12) and failure to receive vaccine (n=12).
Libraries were prepared for sequencing using Illumina's Nextera DNA Library Preparation kit, following the included protocol with no modifications.
This included protocol approval by the University of Cape Town research ethics committee and the UMDNJ Institutional Review Board IRBB).
Other reasons for discontinuing participation in the study for individuals assigned to liraglutide included protocol deviation (n = 1) and elective back surgery (n = 1).
The MITT analysis was more inclusive than the PP analysis because it included protocol violators, and RVGE episodes regardless of serotype immediately following dose 1.
This included protocol safety guidelines about rosiglitazone use and discontinuation that were consistent with the drug's FDA-approved prescribing information (package insert).
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Two time points were abstracted for the analysis from all included protocols and their subsequent reviews.
Another editorial inconsistency was the finding that 7% of the included protocols had two unique identification numbers.
Secondary end points included protocol-defined COPD exacerbations, mortality, AEs, and serious AEs (SAEs).
18 In the present study, we included protocols regardless of publication status.
We are extracting data on RCT characteristics and planned recruitment for all included protocols.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com