Rats have far greater inter-sex metabolism differences than do many other species, including humans, so marked differences in response between sexes at a given dose resulting from differences in metabolism are not uncommon (Mugford & Kedderis, 1998).
The DIS approach conferred additional advantages, including a marked difference in the number of days during which patients were awake and following commands (85.5% versus 9.0%; P < 0.001).
Two retrospective studies have included relatively large numbers of patients and showed marked differences in the best response to retreatment with bortezomib [ 8, 9].
F. tularensis includes 4 subspecies (F. tularensis subsp. tularensis, F. tularensis subsp. holarctica, F. tularensis subsp. novicida, and F. tularensis subsp. mediasiatica), which show marked differences in many epidemiologic features, including geographic distribution, virulence, and genetic diversity (3 ).
The lower penetrance figures are seen with CNVs that show less marked differences in frequencies between cases and controls, including distal 16p11.2 duplications, 16p12.1 deletions, and 16p13.11 deletions.
On average there were no marked differences in socio-demographic factors across the three countries included.
There are three buzzard morphs which show marked differences in melanin coloration and many other traits including parasite load and aggression [24], [25].
There were no marked differences in reach of campaign components in the three age groups, and the findings have therefore not been included in the tables below.
What Bill Bradley calls the luck of being the son of these parents arises from the marked differences in their personalities.
