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It is the first time that a section on hunger has been included in the guidance.
In some cases, it may be possible to measure toxicity and bioaccumulation under more realistic conditions in field and semi-field systems and these lines of evidence should also be included in the guidance.
A key difference between these is the recommendation for the use of weight of evidence for assessment of properties relevant to the categorization of substances for P, B, and T. We believe that the use of a formal, quantitative, and transparent process of weight of evidence should be included in the guidance for the selection of appropriate data and how these are compared to the criteria.
A separate section is included in the guidance which helps identify both intrinsic and extrinsic factors that may predispose to injury.
Participants at a September 2010 workshop hosted jointly by the World Health Organization (WHO)'s Cost-effectiveness and Priority-setting (CEP) unit in Geneva, Switzerland, the International Society on Priorities in Health Care, and the University of Bergen, reviewed results and refined concepts to be included in the guidance.
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A very similar stipulation is included in the latest guidance.
The testing of light boxes is included in the QC guidance for SFM systems [11, 12, 16].
They have attracted significant interest in recent years [27] and are also included in the revised guidance of the US Food and Drug Administration FDAandand the European Medicines Agency EMAA) [28] for the approval of drugs.
This temperature of 12°C is also included in the draft 'Guidance on the assessment of persistent, bioaccumulative and toxic (PBT) or very persistent and very bioaccumulative (vPvB) substances in veterinary medicine' [22].
Interestingly, none of these factors is included in the National Institute for Health and Clinical Excellence guidance for prescribing biological therapies in RA.
There is no checklist currently in Ireland for Irish hospitals to assess how prepared they are for an influenza pandemic, not included in the Irish guidance for an influenza pandemic.
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