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A careful analysis revealed that those probes with discordant results were often derived from genomic sequences that were not included in all transcripts of a given gene.
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"That's not the way decisions about who is in and out of government should be made". The comments were not included in a transcript of Mr Cable's conversation with the undercover reporters published earlier on Tuesday by the newspaper.
Based on the genome annotation, all of the 6 genes included in the transcripts of INV-CTYp and the 4 genes included in the transcripts of INV-INVp were found to be down-regulated.
In TCF12 and OSBPL1A, the expression follows the pattern of already described short and long transcript isoforms, and for alternative splicing to explain this pattern, novel extreme 5' start exons would have to be included in the transcript of both genes followed by alternative splicing of at least eight otherwise constituve spliced exons, a scenario we consider highly unlikely.
This result suggests that, on average, the transcript levels of the genes included in the singleton dataset are lower than those included in the assembled contigs.
(The remark was not included in the official transcript of the interview).
It further suggests that most of these elements are not included in transcripts or proximal promoters of documented genes.
Blocking these enhancer sequences could reduce the amount of PE44.1 included in mature transcripts.
Then my father took me away" (independent translation) Similarly, the example below shows the differences in the level of detail included in the transcripts.
Most transcripts detected with Method 1 (no depletion_Affymetrix) were included in the set of transcripts detected with Method 2 (Globin PNAs_Affymetrix) (98.6%); only 40 probe sets met the detection filtering criteria exclusively in Method 1 (no depletion_Affymetrix) samples, all of which were associated with low probe set signal intensities.
In the case of exon 7, the 12-nucleotide alternative sequence was included in 80%% of the transcripts in whole adult brain and nearly all of the transcripts in the liver and kidney (~95 %).
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