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These disadvantages include the necessity of shipping samples to a laboratory for analysis, the complex experimental procedures, and equipment needed to perform the testing [7].
Implications for experimental design of animal studies of developmental exposures to neurotoxicants include the necessity of a 'no behavioral experience' group, given that epigenetic changes in response to behavioral testing can confound effects of the neurotoxicant itself.
Lessons learned from this include the necessity of good financial management, the importance of marketing and outreach, the use of short and simple development steps, and the need for comprehensive contingency planning.
Implications include the necessity of wakefulness monitoring and modeling, taking measures to maintain a state of wakefulness, acknowledging the possibility of sleep and exploring its consequences, and especially the critical assessment of possible false-positive or false-negative results.
The Irish Times reports that Facebook's grounds for appeal to the Supreme Court in the Schrems II case include the necessity of the High Court making a reference in light of Privacy Shield — with the company arguing the court is bound by the finding on US law contained within the Privacy Shield decision.
These conditions include: the necessity of choosing seriously and inwardly; commitment to the belief that predications of good and evil of our actions have a truth-value; the necessity of choosing what one is actually doing, rather than just responding to a situation; actions are to be in accordance with rules; and these rules are universally applicable to moral agents.
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However, there are significant potential drawbacks to use of the baculovirus expression system: these include the necessity for constant maintenance of baculovirus stocks, the need for fresh batch infections to be made each time the product is required, and co-purification of recombinant baculovirus or baculovirus proteins with VLPs.
However, the sensitivity to change is not yet established and the disadvantages of CT include the necessity for ionising radiation and inability to visualize soft tissue.
He learned a lot from the example set by the Nabis, including the necessity of departing from it.
The result was a script that often drew big laughs in Oregon last year, despite its heavy themes, including the necessity of grieving and the inability of some people to do so.
There were technical problems, including the necessity of carrying three cameras bolted together at the correct angles on the toboggan or other carrier, synchronization of the three separate films, and matching of the image structure and brightness at the joining edges on the screen.
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