CFD offers advantages that include substantial reduction of lead times and costs of new designs, the ability to study systems where controlled experiments are difficult to perform, and the ability to study systems under hazardous conditions at and beyond their normal performance limits.
Measurable benefits also include substantial reductions in out-of-pocket costs among beneficiaries.
The increased burden (including substantial legal costs) with proving one's innocence can result in owners abandoning rightful claims to seized property.
As a highly prevalent neurologic disorder, migraine headache exerts a considerable burden on individuals and society [1, 2], including substantial economic costs [3].
These projects are on course to cost up to £9bn because they include substantial private maintenance contracts lasting for up to 30 years.
Fitch noted that the country's general government deficit for 2010 would be equivalent to about 32 percent of gross domestic product, though it noted that included substantial one-off costs booked for the issue of promissory notes by the state to the banks.
But his auditors concluded that the government appeared to have both understated the likely purchase price — the 9 billion Canadian dollar estimate — and not included several substantial costs directly related to the program.
The estimated monetary cost of the floods to the insurance industry was in excess of £3 billion, not including other substantial costs that were met by central government, local private bodies, businesses and individuals [ 13].
In addition to the clinical burden of AD experienced by individuals (François et al., 2014), AD has wider societal consequences, including substantial direct and indirect economic costs (Rehm et al., 2012, Laramée et al., 2013).
Yet, federal agencies operating under laws directing them to protect national interests—are now issuing regulations with significant costs to U.S. residents and citizens based on a finding that benefits, including substantial benefits to foreigners, "justify" those costs.
Expenditures for utility devices, which may well have included substantial out-of-pocket expenditures, amounted to 10.1% of direct costs.
