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Mechanisms to explain aberrant de novo methylation in these contexts include (a) targeted recruitment of DNA methyl-transferases by cis-acting factors such as G9a or EZH2 [ 14], or (b) loss of boundaries or "protective" transcription factors leading to the spread of DNA methylation into affected regions in the genome [ 15, 16].
Essentially, if you write an extensive blog post, or provide a quick checklist – basically, any blog posts that help solve a problem for your target audience – you can also include a targeted content download to go with your blog post in order to generate more leads.
The crude coupling product obtained was confirmed to include a targeted dumbbell polymer in addition to unreacted L-80 and R-30, and a single-tail tadpole polymer as byproducts.
Additionally, the opportunity to include a targeted drug release functionality is presented.
(a) This section of the report should include a targeted, systematic and comprehensive description of all abnormalities and should start with those features that are relevant to the clinical request or suspected pathology.
With a number of militant organizations, conceived on ethnic lines - and often supported by external elements - operating in Iran and posing a threat to national security and unity, Tehran's countermeasures should include a targeted strategy of winning the hearts and minds of the country's ethnic minorities in order to strengthen their loyalty to land and country.
Similar(49)
These systems can be modified to include a targeting peptide for a specific cell type, such as airway epithelial cells [ 31].
Last month the government published long-awaited plans to improve air quality, including a "targeted" scrappage scheme to take the most-polluting vehicles off the road.
Similar to the grassroots designs, the methodology includes a targeting and an optimisation stage and accounts for the simultaneous use of thermodynamic principles and mathematical programming.
The UN's millennium development goals include a target to provide sanitation to the world's 2.6 billion toiletless by 2015.
The proposed sustainable development goals, set to come into force in January, include a target to eliminate child marriage by 2030.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com