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The endothermic enthalpy relaxation peak, characteristic of aged glasses, could be erased at temperatures well below Tg by large mechanical deformations, i.e. close to the incipient strain hardening level in uniaxial compression tests.
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We show that recent extensions of this model can detect incipient strains one year or more in advance of their dominance in the human population.
Both simulation and application use data from two real populations: the incipient strains of the Collaborative Cross (pre-CC) (Aylor et al. 2011) and the Northport HS mice (Valdar et al. 2006a).
We continued to produce backcrosses till the N7 generation, an incipient congenic strain containing only 0.8% of the donor C57Bl/6 genetic background and 99.2% of the recipient FVB/N genetic background.
Incipient congenic strains consisting of different portions of the chromosome 4 QTL from BALB/cByJ on a CBA/CaH background, and vice versa, were produced using a marker-assisted breeding scheme.
Infection challenges of the Chr4 incipient congenic strains confirmed detection of the Spir2 QTL observed in the CCBAF2 mice, but did not reduce the size of the critical region.
Early detection of incipient dominant influenza strains is one of the key steps in the design and manufacture of an effective annual influenza vaccine.
By saturated, we refer to frictional systems for which all particle contacts involve sliding friction, which is relevant for certain frictional models and the study of incipient flow and stress-strain hysteresis.
Specifically, CC founder strains and incipient lines of the CC were sensitized and challenged with house dust mite allergen followed by measurement of granulocyte recruitment to the lung.
Mice from the Tau4RTg2652 line used in these studies were backcrossed 6 9 generations (incipient congenic) with the C57BL/6J strain.
We surveyed hematological parameters in the eight CC founder strains and 131 incipient lines of the CC (pre-CC).
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