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Using exome sequence data from 159 families participating in the NIH Undiagnosed Diseases Program, we evaluated the number and inheritance of reportable incidental sequence variants.
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Every "Nutcracker" choreographer at some point imposes a scenario different from the one Tchaikovsky was illustrating, but Mr. Morris goes much further than most, and there are incidental sequences in which his scenario grows overambitious and perplexing.
Following the ACMG recommendations for reporting of incidental next generation sequencing findings, we extracted variants in 56 genes from the exome sequence data of 543 subjects and determined the reportable incidental findings for each participant.
Recently, American College of Medical Genetics and Genomics recommendations for reporting incidental findings in sequencing have suggested that bioinformatic predictions are not sufficient to declare clinical significance.
A comparison between sources revealed fewer plastome-related reads from root-derived template but an increase in incidental bacterium-derived sequences.
Middleton et al., in their study of the attitudes toward the return of incidental results from sequencing research, note that, "…genetic health professionals and genomic researchers agree that ancestry is not a category of data for which it is appropriate to search for and to share," yet the members of the public they interviewed showed more interest in this information [ 45].
Yet, technically, it is not an opera but a sequence of incidental music, songs and masques for a ramshackle Restoration adaptation of A Midsummer Night's Dream.
The advantage of using a microarray platform to genotype a defined set of SNP loci for karyomapping is that there are no incidental findings at the sequence level.
A little over one month ago, on March 21, the American College of Medical Genetics and Genomics (ACMG) announced a set of recommendations on incidental findings in clinical sequencing.
The ACMG recommendations on incidental findings in clinical sequencing are the first by any professional organization to acknowledge that genomic analysis should be aligned with the standard practice of medicine and point the way to an exciting future in which genomic information will begin to fulfill its lifesaving potential.
The music for the episode both for the TGS sequences and incidental underscore was provided live by the SNL house band under the direction of Fey's husband Jeff Richmond and Leon Pendarvis.
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