Suggestions(1)
Exact(17)
That study randomised women, aged 50 62 years, with a normal prevalent screen in the UK National Health Services NHS Breast Screening Programmeme, to a conventional incident screen after an interval of 3 years (control arm) or to three annual screenings (study arm).
True FNA: 11/13 incident screen, 2/13 prevalent.
The publication also announced the introduction of two-view mammography at the incident screen.
An incident screen with create, update and search utilities was designed and completed in May 2011.
The incident screen collects incident, disease- and event/facility-specific data, case definition and coordinator/investigator information.
Subsequent interval cancers occurring most commonly during an incident screen in women aged 50 to 59 years, 12 to 24 months following NHSBSP screening.
Similar(43)
The introduction of two-view mammography at incident screens is associated with a reduction in incidence of interval cancers.
Incidence rates decreased at the incident screening, but they did not return to the predicted incidence rates.
Compared to the performance of incident screening mammography alone, addition of prevalent MBI significantly increased cancer detection rate from 3.2 to 10.7 cancers detected per 1,000 women screened [3].
Investigators planning these trials need to know how the study design, particularly the length of accrual, the number of incident screens, the length of follow-up, and the method used to interpret the screening test, affect sample size requirements.
Incident screen-detected breast cancer histologies were notified separately by the ONS and NHSBSP.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com