Sentence examples for incidence substantial from inspiring English sources

Hospitalization for AHF remains a major clinical challenge, with a high and increasing incidence, substantial morbidity and mortality, and few improvements in therapy over recent decades.

Stable or falling mortality alongside rapidly increasing incidence suggests substantial gains in survival.

The difference in the incidence is substantial for HL, NHL and MM (2·5- to 5-fold), whereas the leukaemias (AML, ALL and CML) have a more similar incidence.

Overall, our findings indicate that B. pertussis incidence is substantial in adults aged ≥50 years that considerably exceeds the generally reported disease incidence.

Despite the high incidence of substantial anterior femoral notching in our series (41%) and the series published by Ritter et al. (2005) (27%), there was a very low incidence of supracondylar fracture of the femur (0.5%).

If this underestimate of incidence were substantial, tegaserod effects on gallbladder surgery could be obscured (biased toward a null finding), but this effect would be considerably less pronounced for the outcome of general abdominal surgeries so the consistency of study results for these two outcomes is reassuring.

Though this was not statistically significant, halving this incidence may have substantial clinical impact.

Recent studies show a substantial incidence of Pneumocystis jirovecii colonization and infection in patients with chronic inflammatory lung conditions.

The 0.5 arcsec angular resolution of the Chandra X-ray Observatory is possibly the best that a grazing incidence telescope with substantial collecting area will ever attain.

Nonetheless, better recognition of the substantial incidence of childhood-onset bipolar disorder in the United States and earlier initiation of appropriate psychosocial (Miklowitz et al, 2013) and pharmacological treatment may be life saving.

However, since the blood clotting mechanism is compromised by the use of thrombolytic agents, such as t-PA, there is a substantial incidence of bleeding during and following stent implantation that can be fatal.