Protection of amifostine against immunological toxicity may therefore account for the reduced incidence of asthenia noted in the present study.
As such, we conservatively chose a high incidence of 10% (note that, for example, the lifetime incidence of cervical cancer is less than 1%[ 17]).
Incidence of infections noted with Itolizumab therapy was less compared to placebo group (arm A, 11.1%; arm B, 8.9%; Placebo group, 18.6%).
A critical assessment of immune-mediated HIT suggests a frequency of 0.2 5.0% in patients exposed to heparin for more than 4 days with an overall incidence of 2.6% noted in a meta-analysis [ 4].
In the study cohort, some of the reduction in the incidence of illness noted after November 1999 among Loch Lomond zone residents might have been attributable to reduced environmental exposure, associated with the FMD outbreak.
The incidence of CHF noted in this trial is actually numerically lower than that reported in a smaller phase II trial of dose-dense AC therapy followed by THL reported by Dang et al. [ 27].
The incidence of epilepsy noted among these VA patients aged 66 years or older (156 cases/100,000 patients) is well above the range in population-based studies reviewed by Banerjee and colleagues, 16-51 per 100,000 [ 3].
Also, an attenuated response of urinary NGAL was found in adult cardiac surgery patients in whom a lower incidence of AKI was noted when sodium bicarbonate was administered instead of sodium chloride [34].
In 4 (out of 6) animals treated with 1.75% hyaluronan thiomer gel (HA gel), an increased incidence of swelling was noted at the surgery site only at some time points and in some animals with an increased body temperature (39.5 °C) and reduced food consumption.
Dozens of observational studies have shown an association between moderately increased homocysteine levels and the incidence of cardiovascular diseases, noted epidemiologist Petra Verhoef of the Wageningen Centre for Food Sciences in the Netherlands, who spoke on 18 February at the meeting of the American Association for the Advancement of Science (ScienceNOW's publisher).
A higher incidence of injuries was noted during the first than in the second half of the study period (4.67 versus 2.29 per 100 FTEYs, p = 0.005).
