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Higher incidence led to more prevalent cases and higher cost.
The inclusion of the impact on HZ incidence led to less cost-effective results.
These variations in eBL incidence led us to hypothesise that other environmental factors were affecting the risk for eBL.
However, in this study where there is low PTB + CDR (63%) and high prevalence rate of HIV among TB patients (9.4%), it is not convincing to argue that the decline in TB incidence led to stability in PTB + case detection rate after six years of DOTS implementation.
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The reasons for the findings are unclear, but the authors say it may be that hormonal changes of menopause lead to a reduction in bone mineral density and that fracture incidence leads to increased mortality risk.
An underestimation of the future incidence leads to an underestimation of the cost of head and neck cancer.
Only four studies with iron cosupplementation reported mortality outcomes, and evidence of outcome reporting bias for diarrhoea incidence leads to cautious interpretation of differences in this outcome.
6 An examination of the effects of malaria on female educational attainment in Paraguay and Sri Lanka found that every 10% decrease in malaria incidence leads to 0.1 years of additional schooling, and an increase in the chance of being literate of 1 2% points.
However, the complex interaction among increasing incidence, lead time, age at diagnosis and calendar period of diagnosis is often poorly appreciated (Paci and Duffy, 2005).
These incidence rates led to a protective effect of 61.0% (95% CI: 21.0% to 82.7%).
In our study, treatment with metformin did not affect total tumor incidence, but led to the increase in the mean life span of tumor-bearing mice.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com