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When case fatality is high, mortality rates may be greater than contemporary incidence rates if (i) incidence is falling rapidly, (ii) incident cancer cases are under-ascertained, (iii) mortality is over-ascertained, or (iv) incident cancer cases are under-ascertained to a greater degree than contemporary cancer deaths.
While asthma incidence is falling, the absolute number of prevalent cases will continue to rise.
12 More concerning are the trends for cerebrovascular disease, where the incidence is falling by 12% in high income countries and increasing by 12% in low and middle income countries.
7 Malaria incidence is falling in some areas, and the problem of overtreatment becomes more important where malaria incidence is decreasing because the proportion of serious causes of febrile illness that are not malaria increases.
The incidence of CF in the general United States population has been approximately 1/3500 live births, however this incidence is falling, perhaps as a result of preconception and prenatal screening offered to the general population in order to identify carriers of cystic fibrosis [ 7].
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Next Professor Nutt claims that the incidence of schizophrenia is falling while consumption of skunk has been rising.
Although the global incidence of TB is falling, the burden of disease is still high, especially in low- and middle-income countries (LMICs) where it is associated with poverty (WHO 2013).
Although worldwide its incidence in childhood is falling, due to widespread immunization against hepatitis B, it remains a difficult problem as chemotherapy has made little or no impact on survival and most tumors are unresectable.
It is estimated that while the incidence of HCV is falling in many healthcare systems, the peak consumption of healthcare resources is yet to come as increasing numbers of patients with HCV develop complications of their chronic viral hepatitis [ 16, 29].
Restrictions on animal movements were imposed on nearly 1,000 farms in northeastern England after 17 cases of foot-and-mouth disease were confirmed in Yorkshire Dales National Park, a major tourist area, at a time when the incidence of the disease is falling elsewhere in Britain.
But brain death is relatively uncommon, and the incidence of brain death is falling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com