Using the standardized worksheet for the incidence estimation, the estimated Hib meningitis incidence among children < 5 years of age was 9.8/100,000 (95% CI, 6.5-14.8) in Hanoi and 22.5/100,000 (95% CI, 18.4-27.5) in Ho Chi Minh City.
For incidence estimation, we adopted a Bayesian approach to estimate the MI ratios.
The cumulative incidence estimation methods outlined above are nonparametric, that is, these estimates are not based upon any specific model.
We observed 4,869 individuals over 7,685 person-years for longitudinal HIV incidence estimation.
It is evident that much work is still needed in the area of assay-derived incidence estimation.
Several approaches have been used for measuring HIV incidence in large areas, yet each presents specific challenges in incidence estimation.
Based on this incidence estimation, they made various AIDS impact projections for high and low scenarios from 1991 to 2000 using Demproj and AIM (Table 1).
Several countries, Thailand included, are supplementing national surveillance for HIV infection by using BED-based incidence estimation while incorporating elements of case-based surveillance.
It is thus important that the parameters necessary for HIV incidence estimation are calibrated using data from those settings where longitudinal follow-up is available.
The promise of the cBED assay for HIV surveillance, program evaluation and policy making, lies in the fact that it allows HIV incidence estimation from cross-sectional samples.
The cBED assay performs well in HIV incidence estimation if the locally measured long-term FPR is used, but significantly underestimates incidence when a FPR estimate based on previous studies in other settings is used.
