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It has been unclear whether the failure to translate promising results from animal studies in AKI into successful human trials has been caused by lack of therapeutic efficacy or inappropriately delayed application of the intervention.
Prolonged exclusive breastfeeding can potentially cause energy and nutrient deficiencies when introduction of complementary foods is inappropriately delayed.
The withholding or withdrawal decision was considered by physicians to have been timely in 79% of cases and inappropriately delayed in 21%.
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But councils found to be inappropriately delaying the discharge of hospital patients will not have to pay fines until January 2004.
Conversely, if low risk patients are seen urgently, it may inappropriately delay high risk patients.
Reports that some participants wore wristbands inappropriately, and/or delayed completion of trial paperwork could represent confounding variables and have implications for the trial results, and the design of clinical trials within the field of cancer.
The fact some patients wore wristbands inappropriately, and/or delayed completion of trial paperwork are potentially serious threats to the validity of the trial findings, and bring into question the conclusions from this trial [ 17].
In a statement released on Friday, James Bullard, the head of the Federal Reserve Bank of St . Louisand a colleague of Bernanke on the Federal Open Market Committee, said the announcement of the plan to draw down quantitative easing was "inappropriately timed," and should have been delayed until there was more confirmed evidence of a pickup in economic growth.
This statement is supported by previous studies, which claim that the instability experienced by older persons during walking is commonly associated with muscle weakness [ 12], delayed or reduced muscle activations, and inappropriately organized muscle response [ 13].
For example, destruction of GATA1 specifically during mitosis was found to lead not only to delayed reactivation of bound genes but to inappropriately high expression of GATA1-repressed target genes [ 16].
Our results showed that TK1 and other cell cycle genes are inappropriately persistently expressed in emerin null cells during differentiation causing delayed exit from cell cycle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com