Sentence examples for inappropriate trials from inspiring English sources

Two studies in which this was attempted had disappointing outcomes [ 69, 70] that may have resulted from inappropriate trials designs.

However, despite the positive phase II data there remains a high failure rate in late stage clinical trials which, in many cases can be ascribed to inappropriate trial design, poor patient selection and inconsistency in patient management.

We defined a traumatic instrumental delivery as an inappropriate trial of labour with a vacuum extractor or forceps in the following circumstances: incomplete cervical dilatation, noncephalic presentation or cephalic malpresentation, nonengaged fetal head or clear indication of cephalopelvic disproportion.

Complex instrumental delivery was defined as an inappropriate trial of labour in a singleton delivery with a vacuum extractor or forceps in the following circumstances: incomplete cervical dilatation, non-cephalic presentation or cephalic malpresentation, non-engaged fetal head, or a clear indication of cephalopelvic disproportion.

Many seem to assume that lack of significant differences between active interventions demonstrates equivalence, which is inappropriate in trials designed to test for superiority that are neither designed nor powered to demonstrate non-inferiority.

Crossover study designs are thus inappropriate, and trials are usually conducted with a parallel-group design.

Because it is desirable to match the genetic clade of vaccine immunogens to the viruses circulating in clinical cohorts, the AIDSVAX B/E rgp120 vaccine used in Thailand in the RV144 trial is considered inappropriate for clinical trials in Africa, India, or China, where clade C viruses account for the majority of new infections (UNAIDS, http://www.unaids.org).org

Despite guidelines recommending the use of formal tests of interaction in subgroup analyses in clinical trials, inappropriate subgroup-specific analyses continue.

We had planned to conduct a meta-analysis but this was not possible, owing to the heterogeneity of study interventions and outcome measures, which made pooling of data across trials inappropriate (I2 values of 89% to 99%).

"To allow the defense to address sexual-history matters of a victim at preliminary hearing, in open court, which are later deemed inappropriate evidence at trial would completely abrogate the Rape Shield Statute and its purpose," Deputy District Attorney Ingrid S. Bakke wrote in a motion filed Tuesday.

Nevertheless, recent studies have shown that transparency is impaired by non-publication or inappropriate publication of trial results.