However, a maxim in developmental biology and pediatric medicine is that it is inappropriate to use effects in adults to predict effects during development (i.e., babies are not little adults) (National Research Council 1993).
Update: On Friday, during an interview with CNN, EPA administrator Scott Pruitt said that it was inappropriate to discuss the effect of climate change on the intensity of Hurricane Irma.
However, the growth of these cells had no significant alteration, whatever promotion or suppression of cell growth, implying that those HCC cell lines could be inappropriate to evaluate the effect of SFRP1 on cell growth.
In the field of health services, it seems inappropriate to monetize health effects as done in cost-benefit analysis (CBA).
There may be legitimate objectives underlying the government actions creating these policy barriers, but it would be inappropriate to evaluate the effects of private sector response to liberalization in such environments.
Many RCTs are restricted to selected subgroups of the population, and it is generally inappropriate to extrapolate adverse effects data from such studies to the wider population, which includes more vulnerable people, e.g. those with co-morbidities, co-medications.
48 The evolving context and inability to control the environment in which the programmes will be evaluated render the use of an experimental design inappropriate to evaluate quantitative effects (use of services and quality of life).
As rapalogues interfere with glucose metabolism using mechanism independent of their antitumour effects, 18-FDG PET scan appears inappropriate to reliably monitor the effects of rapalogues (O'Donnell et al, 2008).
Because the effects of migration on prey density are scale-dependent (i.e., local-scale changes in prey density might yield no detectable density differences at the landscape level), it would be inappropriate to calculate a 'mean' effect size across studies spanning an array of different spatial scales [51].
It would also be inappropriate to conclude that an effect on deaths prior to a specified number of hours or days necessarily implies that TXA works by reducing bleeding as opposed to reducing inflammation.
