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Therefore, the possibility that the Fab-bound LeuT mutant structure may be an inappropriate template in this regard cannot be ruled out, implying an overly extreme movement of TM1a.
One possibility is that SCE rate is very low in the normal context because inappropriate template choice within a sister chromatid leads to unequal SCE leading to gene duplication or deletions, which are associated with tumorigenesis [ 71].
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We assessed the effect of using nationality appropriate and inappropriate templates for tissue segmentation on the volumetric changes of GM and WM for Chinese participants.
Conversely, the nationality-inappropriate templates and the adult templates were significantly different in nearly all cases for the Chinese children participants.
We evaluated the effect of using nationality-appropriate and nationality-inappropriate templates on the volumetric changes of GM and WM over development.
We assessed whether registrations based on these Chinese age-specific templates would fit Chinese children's MR images significantly better than nationality-inappropriate templates based on U.S. children, or adult templates based on either Chinese or U.S. adults.
We predicted that the use of Chinese age-specific templates with Chinese children's MRIs would result in significantly less deformation and more consistency between original and transformed images than the use of other age-or nationality-inappropriate templates.
The internal and external consistency tests showed that the global shape and size of the Chinese children's brain images changed significantly after registration into the nationality-or age-inappropriate templates.
The ratios of width:length, height:length, and height:width were also significantly different between the original images and the registered images into the age-or nationality-inappropriate templates, meaning the shape of the brain differed between the Chinese participants' brain and the U.S. children and both adult templates.
Larger changes in brain size were required to register the Chinese or U.S. children's images into the nationality-inappropriate child templates or adult templates.
We compared the consistency of brain shape and size between the original brain images to four different types of average templates including the nationality-appropriate child templates, nationality-inappropriate child template, Chinese56 adult template, and the US20 24 adult template.
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