Sentence examples for inappropriate proliferation from inspiring English sources

Inappropriate proliferation and extracellular matrix degradation produce a tissue mosaic instead of a compartmentalized, stratified epithelium.

Mutated cell survival and inappropriate proliferation, disrupting this balance, would be expected to contribute to oncogenesis (Wyllie, 1997).

The nature of these genes suggests that loss of BRCA1 could lead to inappropriate proliferation, consistent with the high mitotic grade of BRCA1-associated tumours.

Thus, CEH-20 and UNC-62 act redundantly in V lineages, but non-redundantly in H lineages, to prevent inappropriate proliferation.

These controls are needed to both ensure the integrity of the body plan and to restrict inappropriate proliferation that could lead to cancer.

Cancer is caused by metabolic changes in cells that lead to DNA damage that can fuel the uncontrollable and inappropriate proliferation of cells.

Misregulation of the cell cycle machinery can lead to inappropriate cell proliferation, as often seen in neoplastic disease.

Given the association of BMPR2-associated PAH with inappropriate cellular proliferation, we investigated the impact of stimulating with a known mitogen (PMA) on BMPR2 gene expression [ 32].

Impairment of ciliary length control and ciliary assembly can lead to inappropriate cell proliferation and defects in signal transduction, causing ciliopathies and perhaps tumorigenesis.

In Drosophila, Scribble (Scrib), Discs large (Dlg) and Lethal giant larvae (Lgl), cooperatively establish and maintain apico-basal cell polarity and repress inappropriate cell proliferation and neoplasia (invasive overgrowth with a failure to differentiate) in both epithelial and neuronal tissues [ 1].

Epistasis analysis suggests that ceh-20 and unc-62 act upstream of rnt-1 to repress inappropriate seam cell proliferation in daughters destined to differentiate.