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The exclusion criteria were: treatment with amikacin within 7 days prior to inclusion; inappropriate dose of amikacin (<27.5 or >32.5 mg/kg); inappropriate duration of amikacin infusion (<25 or >35 min); and inappropriate delays in measuring the amikacin C max (<20 or >40 min after the end of infusion).
32 admissions were inappropriate and 83 were for an inappropriate duration.
or an inappropriate duration of insulin delivery, rather than an error in the carbohydrate-to-insulin ratio per se.
PIPs were categorized as: Potentially inappropriate medication; Potentially inappropriate duration; Potentially inappropriate dosage; and Potentially inappropriate drug-drug interaction.
Thirty-five percent of patients were prescribed antipsychotics and 22.9% had benzodiazepine for potentially inappropriate duration, defined as more than a month [ 32].
Most common PIPs were drug interactions (33.9% of treated patients), followed by potentially inappropriate duration (23.6%), potentially inappropriate medication (14.7%) and potentially inappropriate dosage (9.6%).
Similar(47)
In addition to wrong dosages, inappropriate durations of treatment were also identified.
Also, there were cases of subtherapeutic dosages and inappropriate durations of treatment.
However, inappropriate prolonged duration, of SAP administration, for more than 24 hours were noted in 69% of patients.
PIM has been defined as the use of medication with risk greater than benefit, inappropriate dosing duration, prescriptions that lead to clinically significant drug drug and drug disease interactions, and the under-use of potentially beneficial medications.
Up to half of the antibiotic use is unnecessary or inappropriate, and excessive duration is the greatest contributor to inappropriate use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com