Your English writing platform
Discover LudwigExact(5)
This isn't about the ordinary quality-of-service risks of cloud computing such as downtime; these are user experience risks of relying on external policies and practices that could be considered censorship or inappropriate aggregation with data from sites you haven't even heard of.
Indeed, the inadequate or inappropriate aggregation of data is another potential source of spatial inconsistencies.
Numerous neurodegenerative and neuromuscular diseases are associated with inappropriate aggregation of ubiquitinated proteins and GSK3 (glycogen synthase kinase 3) activity is involved in several of these proteinopathies.
For example, the common missing elements in systematic reviews, in general, are: explicit search strategy; explicit articulation of exclusion criteria; absence of quality assessment of the underlying studies; and inappropriate aggregation of study results[ 32].
Protein concentration is also a key issue which could affect refolding, on the one hand because G6PD exists in a rapid dimer-tetramer equilibrium, affected by pH and ionic strength [ 25], and on the other hand because too high a concentration may encourage inappropriate aggregation.
Similar(55)
Thus, neo-synthesised HSP chaperone proteins and an increase in HSPs helps to limit misfolding and inappropriate aggregations of other proteins in cells exposed to stress.
The Hsps, in particular the 70 kDa (Hsp70) family, are constitutively expressed in cells under normal (non stressful) conditions and function as molecular chaperones, to keep other proteins from forming inappropriate aggregations.
In TTP, abrogated ADAMTS13 activity leads to the accumulation of uncleaved large multimers of von Willebrand factor, which in turn causes inappropriate platelet aggregation and endothelial damage.
Elucidating the involvement of the polyribosome in inappropriate protein aggregation could uncover it as a novel translational target for therapies.
Generally, HSPs prevent inappropriate protein aggregation and mediate transport of immature proteins to the target organelles for final packaging, degradation or repair.
Although HSPs were first defined as proteins induced by environmental and pathophysiologic stress, they are also implicated in protein-protein interactions, such as folding, translocation, and prevention of inappropriate protein aggregation.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com