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A limitation of this theory, however, is that is does not consider the relative costs of the innate and adaptive components of the immune system in different ecological contexts, so it might inadequately explain allelic variation of MHC over a broad range of natural environments [16], [17].
It is increasingly being recognized that the dichotomous categories of employed/unemployed inadequately explain the current unemployment situation; unemployment must be studied in the context of social assistance programs, temporary employment and other atypical employment situations [ 12- 16].
Otherwise, the results of the meta-analysis may inadequately explain heterogeneity in the included trials due to confounding by the differential presence of undetected or unlabelled components in certain component combinations instead of others, or the presence of effect modifiers that could meaningfully explain heterogeneity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com