Sentence examples for inadequate surrogate from inspiring English sources

Since anemia predictably produces augmented Pv aCO2 and decreased Ca vO2, our hypothesis was that Pv aCO2/Ca vO2 might be an inadequate surrogate for RQ.

Finally, given that Pv-aCO2/Ca-vO2 only had a poor correlation with RQ and a different physiologic behavior, it seems to be an inadequate surrogate for RQ.

Since a progressive hemodilution, which does not compromise aerobic metabolism, will predictably result in increased Pv aCO2 [10] and decreased Ca vO2 [11], our hypothesis was that Pv aCO2/Ca vO2 might be an inadequate surrogate for RQ in isovolemic anemia.

The reasons for these false-positive signals could include inadequate surrogate markers, changes in dose, changes in usual care, changes in inclusion criteria and settings and/or the play of chance between the POP/Phase II and pivotal/Phase III RCTs.

Therefore, these data may suggested that KPS was an inadequate surrogate for HRQOL.

The latter two requirements served to eliminate studies that were exclusively designed to measure organ function over a limited time period since this endpoint may be an inadequate surrogate for mortality in trials of novel sepsis therapies [ 5, 6].

Without the highest level of competence, the others represent inadequate surrogates for what the family and the patient probably want.

Ambient PM concentrations are inadequate surrogates for personal exposure because they are at the group level and comprise only a small proportion of personal exposure, they change over time, and they constitute only a small proportion of a life span.

Chiumello and colleagues found that the plateau pressure and Vt were inadequate surrogates for lung stress and strain due to considerable overlap at both different Vt and PEEP values, and strain was clearly over-estimated when recruitment was computed [ 34].

The most common are the use of standardized low VT or limiting VT to a maximum Pplat [ 1] but, as has been previously shown, both are inadequate surrogates for lung atelectrauma and overdistension [ 23].

MAP is at best a surrogate of inadequate microvascular perfusion in shock.