After examination of patient follow-up data and tumor immunostaining, 53 patients were excluded due to inadequate tumor specimen or poor staining, and 40 were excluded due to causes of death not related to lung cancer, leaving a total of 128 patients in the current analysis.
Despite the remarkable similarity in subcellular receptor distributions discussed above, it should be noted that our Met/MET immunohistochemical stain provides inadequate resolution either to distinguish the staining of axonal versus dendritic elements or to differentiate between multiple sources of axonal afferents, within the neuropil.
Data points/samples were eliminated if any of the following problems arose: EPI vaccine administered less than 7 days prior to blood collection, cultures were contaminated, antibody staining was inadequate, the positive control (SEB) did not induce a response in vitro and acquisition of less than 1,000 lymphocytes.
Unfortunately, this bright punctate staining was inadequate to observe finer spatial organization.
Baseline core biopsies from four patients contained inadequate tissue for ALDH1 staining and were excluded, leaving a total of 119 informative subjects.
Most of these patients received definitive CCRT but not radical resection followed by postoperative CCRT as the curative management, so there may be inadequate tissue for p16INK4A stain.
This is most likely due to the inadequate sensitivity of routine histopathological staining procedure and to the insufficient number of examined lymph nodes (Nicastri et al, 2007).
Furthermore, prolonged or inadequate fixation, thick sections, suboptimal staining, or the presence of extensive necrosis, fibrous or inflammatory stroma, and crush artefacts can considerably hamper the evaluation, clearly suggesting that the definition of easily reproducible diagnostic tools is a major clinical need.
Yet in the dismissal, Judge Michael McShane wrote that OSU's "response to the rapes of Ms. Samuelson and Ms. Tracy was shameful, woefully inadequate, and will remain a dark stain on the history of the institution".
