This was largely due to their design, which resulted either in inadequate specification of animal genotype or a lack of interaction between the genetic and environmental components within each model.
Cross-sectional analysis and inadequate specification of the duration of HTN limit temporal interpretations.
Inadequate specification of intervention procedures, combined with other factors at work within the community of bereavement care investigators, may have resulted in the dearth of published replication studies.
A second possible reason could be due to an inadequate specification of the links between perceived susceptibility and risk taking behaviour in the study questionnaire.
Information limitations included trial details, the length of exposure of many participants (correcting for dropouts), and inadequate specification of the nature and severity of incident depressions.
Uncertainties in models, from limited data through to inadequate specification of factors that influence the exposure-response relationship, will therefore lead to uncertainty as to the precise magnitude of the climate change impact.
A lengthy risk assessment focused exclusively on technical and procedural risks (such as "inadequate specification of requirement by NHS," "information governance and data security requirements [may] change," and even that uptake of HealthSpace accounts would outstrip capacity to process applications 40).
The government cites "lengthy procurement processes, poor specifications, weak logistical information systems, inadequate and unpredictable funding for medicines and inadequate infrastructure," districts overspending on private sector drug purchases, and shortage of pharmaceutical staff as causes of drug stock outs [ 39].
Methodological limitations included sampling and measurement biases, inadequate internal validity of measurement tools, poor specification of testing protocols and limitations in statistical analysis.
