When judgements about the effects of options are based on theories, surrogate outcomes, limited observational studies, inadequate impact evaluations, anecdotal experience or analogies, policymakers should be cautious about implementing them (see example in Table 4) [ 29].
Given the inadequate impact of conventional therapies and the rising incidence of HCC, elucidation of the oncogenic mechanisms underlying HCC development is critical for identifying potential therapeutic targets or modalities.
The sub-themes under challenges faced included; inequitable salaries and recognition of experience, overwhelming responsibilities, lack of stimulating interaction in the workplace, inadequate supervision, impact of HIV and AIDS, limited access to further training, limited career recognition, lack of transparency in recruitment of staff, and discriminatory remuneration.
Primary prevention has proven inadequate in impacting the incidence of skin cancer, thus stimulating the development of chemopreventive strategies.
Poor and inadequate sleep negatively impact cognitive and physical functioning and may also affect sports performance.
As Peter goes on to point out, "Five years later, the Bank's Quality Assurance Group castigated the institution's 'pressure to lend', and pointed to the 'fear that a realistic, and thus more modest, project would be dismissed as too small and inadequate in its impact".
In resource-poor settings, where such treatment was started recently, there is inadequate information about impact of ART on the survival of patients especially in children.
The challenge of developing rigorous HR policy trials in Africa is two-fold: baseline data on unmet needs and priorities of health professionals has not been gathered at significant scale [ 9, 10]; and the existing HR information systems are largely inadequate to measure impact.
There was no group-by-time intervention effect for participants whose BMI was lower than 25 kg/m at baseline, on waist circumference, BMI, or weight (Table 5).> Due to inadequate numbers, the impact of the intervention on cancer survivor or carer status could not be assessed separately.
Because housing is considered critical for sober living, inadequate housing resources impact lengths of stay: [Clients] know if they go back to their homeland there's all the drinking and drug use going on [so they] relocate, [but] sometimes we have people staying three weeks to a month later waiting for housing because of the [lack of] availability and the funding.
Poor maternal health and nutrition, as well as inadequate childhood nutrition, impacts a child's early growth and development, beginning in utero.
